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. 1987 Aug;31(8):1274-7.
doi: 10.1128/AAC.31.8.1274.

Detection of a second mechanism of resistance to gentamicin in animal strains of Escherichia coli

E Chaslus-Dancla, G Gerbaud, J L Martel, M Lagorce, J P Lafont, P Courvalin

Detection of a second mechanism of resistance to gentamicin in animal strains of Escherichia coli

E Chaslus-Dancla et al. Antimicrob Agents Chemother. 1987 Aug.

Abstract

One mechanism of plasmid-mediated resistance to gentamicin in Escherichia coli strains isolated from animals is due to the synthesis of the aminoglycoside 3-N-acetyltransferase type IV. A second mechanism of plasmid-mediated resistance to gentamicin was detected in animal strains of E. coli in France and is due to the production of the aminoglycoside 3-N-acetyltransferase type II. The molecular relationships among plasmids encoding this enzyme were studied.

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