Vitamin D Update
- PMID: 33078087
- PMCID: PMC7556559
- DOI: 10.1007/s13671-020-00315-0
Vitamin D Update
Abstract
Purpose: The goal of this review is to provide an update in the field of vitamin D, in particular, the role of vitamin D in non-skeletal health, the complexity of providing patient guidance regarding obtaining sufficient vitamin D, and the possible involvement of vitamin D in morbidity and mortality due to SARS-CoV-2 (COVID-19).
Recent findings: In addition to bone health, vitamin D may play a role in innate immunity, cardiovascular disease, and asthma. Although rickets is often regarded as an historical disease of the early twentieth century, it appears to be making a comeback worldwide, including "first-world" countries. Broad-spectrum sunscreens (with high UVA filters) that prevent erythema are unlikely to compromise vitamin D status in healthy populations.
Summary: New attention is now focused on the role of vitamin D in a variety of diseases, and more individualized patient recommendation schemes are being considered that take into account more realistic and achievable goals for achieving sufficient vitamin D through diet, supplements, and sun behavior.
Keywords: Osteomalacia; Pigmentation; Rickets; Sunscreen; Ultraviolet light; Vitamin D.
© Springer Science+Business Media, LLC, part of Springer Nature 2020.
References
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- DeLuca HF. Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr. 2004;80(6):1689S–96S. 10.1093/ajcn/80.6.1689S. This is a generally helpful primer on the classic functions and understanding of vitamin D. - PubMed
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- Brustad N, Garland J, Thorsen J, Sevelsted A, Krakauer M, Vinding RK, et al. Effect of high-dose vs standard-dose vitamin D supplementation in pregnancy on bone mineralization in offspring until age 6 years: a prespecified secondary analysis of a double-blinded, Randomized Clinical Trial. JAMA Pediatr. 2020;174(5):419–27. 10.1001/jamapediatrics.2019.6083. - PMC - PubMed
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