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Review
. 2021 Feb;36(1):98-104.
doi: 10.1002/ncp.10591. Epub 2020 Oct 19.

Safety, Tolerability, and Outcomes of Enteral Nutrition in Extracorporeal Membrane Oxygenation

Robert C Davis 2nd  1 , Lucian A Durham 3rd  2 , Laszlo Kiraly  3 , Jayshil J Patel  4
Affiliations
Review

Safety, Tolerability, and Outcomes of Enteral Nutrition in Extracorporeal Membrane Oxygenation

Robert C Davis 2nd et al. Nutr Clin Pract. 2021 Feb.

Abstract

Extracorporeal membrane oxygenation (ECMO) is a supportive care system for patients with respiratory or cardiac failure. Patients requiring ECMO are at risk for significant inflammation, prolonged hospitalization, and acquired malnutrition and sarcopenia. Societal guidelines recommend early enteral nutrition in critically ill patients; however, in this population, optimal timing and dose of nutrition remains unknown and fear of reduced splanchnic perfusion, delayed gastric emptying, and bowel ischemia poses a barrier to appropriate energy and protein intake. This narrative review intends to provide an overview of ECMO, highlight the rationale for nutrition support in this population, and review the safety, tolerability, and outcomes associated with enteral nutrition during ECMO.

Keywords: critical illness; enteral nutrition; extracorporeal membrane oxygenation; nutrition support; patient safety; pulmonary ventilation.

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References

    1. Peek GJ, Mugford M, Tiruvoipati R, et al. Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomized controlled trial. Lancet. 2009;374(9698):1351-63.
    1. Yu Y, Xu D, Fu S, et al. Patients with COVID-19 in 19 ICUs in Wuhan, China: a cross-sectional study. Crit Care. 2020;24(1):219.
    1. Full COVID-19 Registry Dashboard. Extracorporeal life support organization. Accessed June 1, 2020. https://www.elso.org/Registry/FullCOVID19RegistryDashboard.aspx.
    1. Brodie D, Slusky AS, Combes A. Extracorporeal life support for adults with respiratory failure and related indications. JAMA. 2019;322(6):557-568.
    1. Guglin M, Zucker MJ, Bazan VM, et al. Venoarterial ECMO for adults. JACC. 2019;73(6):699-716.

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