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Book

Malignant Salivary Gland Tumors

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan.
.
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Book

Malignant Salivary Gland Tumors

Allen Young et al.
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Excerpt

Salivary gland tumors are a rare group of complex, heterogeneous histologies located in the parotid, submandibular, sublingual, and minor salivary glands of the upper aerodigestive tract. The wide variety of tumor etiology, microscopic histology, growth patterns, and tumor characteristics can make diagnosis and treatment challenging for clinicians. The World Health Organization in 2005 recognized 24 different malignant salivary gland cancers; the most common histologies include mucoepidermoid carcinoma (MEC), acinic cell carcinoma (ACC), adenoid cystic carcinoma (AdCC), carcinoma ex-pleomorphic adenoma (CExPA), and adenocarcinoma.

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Conflict of interest statement

Disclosure: Allen Young declares no relevant financial relationships with ineligible companies.

Disclosure: Oluwafunmilola Okuyemi declares no relevant financial relationships with ineligible companies.

References

    1. Boukheris H, Curtis RE, Land CE, Dores GM. Incidence of carcinoma of the major salivary glands according to the WHO classification, 1992 to 2006: a population-based study in the United States. Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):2899-906. - PMC - PubMed
    1. Goldstein AM, Yuen J, Tucker MA. Second cancers after medulloblastoma: population-based results from the United States and Sweden. Cancer Causes Control. 1997 Nov;8(6):865-71. - PubMed
    1. Horn-Ross PL, Ljung BM, Morrow M. Environmental factors and the risk of salivary gland cancer. Epidemiology. 1997 Jul;8(4):414-9. - PubMed
    1. Milán T, Pukkala E, Verkasalo PK, Kaprio J, Jansén CT, Koskenvuo M, Teppo L. Subsequent primary cancers after basal-cell carcinoma: A nationwide study in Finland from 1953 to 1995. Int J Cancer. 2000 Jul 15;87(2):283-8. - PubMed
    1. Fan CY, Wang J, Barnes EL. Expression of androgen receptor and prostatic specific markers in salivary duct carcinoma: an immunohistochemical analysis of 13 cases and review of the literature. Am J Surg Pathol. 2000 Apr;24(4):579-86. - PubMed

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