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Review
. 2021 Feb:90:11-17.
doi: 10.1016/j.alcohol.2020.10.003. Epub 2020 Oct 18.

Alcohol use disorder: A pre-existing condition for COVID-19?

Kristina L Bailey  1 , Derrick R Samuelson  2 , Todd A Wyatt  3
Affiliations
Review

Alcohol use disorder: A pre-existing condition for COVID-19?

Kristina L Bailey et al. Alcohol. 2021 Feb.

Abstract

Alcohol misuse is long established as a contributor to the pathophysiology of the lung. The intersection of multi-organ responses to alcohol-mediated tissue injury likely contributes to the modulation of lung in response to injury. Indeed, the negative impact of alcohol on susceptibility to infection and on lung barrier function is now well documented. Thus, the alcohol lung represents a very likely comorbidity for the negative consequences of both COVID-19 susceptibility and severity. In this review, we present the known alcohol misuse ramifications on the lung in the context of the current coronavirus pandemic.

Keywords: COVID-19; SARS-CoV-2; alcohol; coronavirus; injury; lung.

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Conflict of interest statement

Declaration of competing interest None.

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