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. 2020 Jul-Sep;35(3):264-266.
doi: 10.4103/ijnm.IJNM_19_20. Epub 2020 Jul 1.

Multifocal Meningioma Recurrence Detected on Ga68-DOTANOC Scan

Nitin Gupta  1 , Abhishek Khare  2
Affiliations

Multifocal Meningioma Recurrence Detected on Ga68-DOTANOC Scan

Nitin Gupta et al. Indian J Nucl Med. 2020 Jul-Sep.

Abstract

Meningiomas arise from meningothelial cells of the arachnoid membranes. They are classified into three grades according to the WHO criteria, Grade I (Benign), Grade II (atypical), and Grade III (anaplastic). Radiological and structural imaging computed tomography (CT) and magnetic resonance imaging are done routinely for defining the location, extent, and follow-up. However, these imaging techniques have their limitations. Since meningiomas have overexpression of somatostatin receptor 2, DOTANOC positron-emission tomography (PET)/CT scan is suggested for their delineation and distinguish postradiotherapy necrosis from recurrence. Here, we present a case where DOTANOC PET/CT scan helped in confirming recurrence postsurgery and radiotherapy.

Keywords: Ga-68 DOTANOC scan; meningioma; recurrence.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Maximum intensity projection image of the brain (a) showing DOTANOC uptake in midline and maximum intensity projection of the whole body (b) showing physiological DOTANOC distribution. Positron emission tomography, computed tomography and fused axial, coronal and sagittal images (c-k) suggestive of DOTANOC avid plaque-like dural-based lesions in left fronto-parietal, left parieto-occipital, and left inferior parietal regions
See this image and copyright information in PMC

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