A rare renal malakoplakia mimicking renal tumor presenting with deep vein thrombosis and bilateral pulmonary embolism in a 58-year-old woman

Abstract

Malakoplakia is an uncommon chronic inflammatory disease that appears as soft plaques in various organs and results from defective macrophage function, which tends to affect immunocompromised and debilitated patients. The pseudotumoral form presentation is rare especially with para-neoplastic syndrome. Preoperative diagnosis of renal malakoplakia in appropriate clinical settings can prevent unnecessary surgery. We present a clinical case of renal malakoplakia in a 58 old woman mimicking a malignant locally advanced renal carcinoma with rare presentation of bilateral pulmonary embolism.

Keywords: Deep vein thrombosis; Malakoplakia of kidney; Michaelis-gutmann bodies; von hansemann.

Fig. 1

Left side: CT angiography with pulmonary embolism, right side: CT scan with left kidney renal mass.

Fig. 2

Left side: Histiocytic infiltrate with von Hansemann cells x100, right side: immunohistochmical staining for CD68 strong reactivity for CD68 is noted in the infiltration of histiocytes.

Fig. 3

Lesion with Michaelis Gutmann bodies intracyoplasmic, Prussian Blue 200x. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)