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. 2020 Dec;405(8):1233-1241.
doi: 10.1007/s00423-020-02012-9. Epub 2020 Oct 21.

Irrigation and passive drainage of pancreatic stump after distal pancreatectomy in high-risk patients: an innovative approach to reduce pancreatic fistula

Olga Adamenko  1 , Carlo Ferrari  2   3 , Jan Schmidt  1
Affiliations

Irrigation and passive drainage of pancreatic stump after distal pancreatectomy in high-risk patients: an innovative approach to reduce pancreatic fistula

Olga Adamenko et al. Langenbecks Arch Surg. 2020 Dec.

Abstract

Introduction: Postoperative pancreatic fistula (POPF) represents the most common form of morbidity after distal pancreatectomy (DP). The aim of this study was to illustrate an innovative technique of irrigation and passive drainage to reduce clinically relevant POPF (CR-POPF) incidence in high-risk patients undergoing DP.

Material and methods: Twelve consecutive high-risk patients received irrigation and passive drainage of the pancreatic stump with a Salem sump drainage after DP. The Salem sump was irrigated with 100 ml/h of Ringer solution for 2 postoperative days (POD). In the case of low-drain amylase and lipase levels on POD 3, the irrigation was reduced to 50 ml/h. Persistence of low-drain pancreatic enzymes on POD 4 allowed for interruption of irrigation and subsequent removal of drainage from POD 7 onward in the absence of evidence of any pancreatic fistula.

Results: Overall, 16.6% of the patients experienced a grade 3 or higher surgical complication. We experienced only one case of POPF: the fistula was classified as grade B and it was managed with radiologic drainage of the fluid collection. We did not experience any case of re-operation nor in-hospital mortality.

Conclusions: Irrigation with passive drainage of the pancreatic stump after DP is an interesting approach for CR-POPF prevention in high-risk patients.

Keywords: Complications; Distal pancreatectomy; Drainage; Fistula; Irrigation; POPF.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Schematic representation of the drainage positioning (SS, Salem sump drainage; CF, Cystofix drainage)
See this image and copyright information in PMC

References

    1. Ferrone CR, Warshaw AL, Rattner DW, Berger D, Zheng H, Rawal B, Rodriguez R, Thayer SP, Fernandez-del Castillo C. Pancreatic fistula rates after 462 distal pancreatectomies: staplers do not decrease fistula rates. J Gastrointest Surg. 2008;12:1691–1698. - PMC - PubMed
    1. Pratt W, Maithel SK, Vanounou T, Callery MP, Vollmer CM (2006) Postoperative pancreatic fistulas are not equivalent after proximal, distal, and central pancreatectomy, J Gastrointest Surg - PubMed
    1. Mendoza AS, Han HS, Ahn S, Yoon YS, Cho JY, Choi YR. Predictive factors associated with postoperative pancreatic fistula after laparoscopic distal pancreatectomy: a 10-year single-institution experience. Surg Endosc. 2016;30(2):649–656. - PubMed
    1. Kelly KJ, Greenblatt DY, Wan Y, Rettammel RJ, Winslow E, Cho CS, Weber SM. Risk stratification for distal pancreatectomy utilizing ACS-NSQIP: preoperative factors predict morbidity and mortality. J Gastrointest Surg. 2011;15(2):250–261. - PubMed
    1. Vanbrugghe C, Ronot M, Cauchy F, Hobeika C, Dokmak S, Aussilhou B, Ragot E, Gaujoux S, Soubrane O, Lévy P, Sauvanet A. Visceral obesity and open passive drainage increase the risk of pancreatic fistula following distal Pancreatectomy. J Gastrointest Surg. 2019;23(7):1414–1424. - PubMed

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