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Book

Menetrier Disease

Meghana Gore  1 , Kamna Bansal  2 , Nagesh Jadhav  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Menetrier Disease

Meghana Gore et al.
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Excerpt

Menetrier disease is a rare disorder characterized by giant mucosal folds in the proximal part of the stomach, diminished acid secretion, and a protein-losing state with hypoalbuminemia. Other names for Menetrier disease are hypoproteinemic hypertrophic gastropathy and giant hypertrophic gastritis.

This condition is common in middle-aged men. The age group affected is generally between 30 years to 60 years. It is less commonly described in females and children. In adults, the condition is often progressive. The etiopathogenesis of Menetrier disease is not entirely understood. It affects mainly the proximal part of the stomach (body and fundus) and spares the distal portion (antrum).

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Conflict of interest statement

Disclosure: Meghana Gore declares no relevant financial relationships with ineligible companies.

Disclosure: Kamna Bansal declares no relevant financial relationships with ineligible companies.

Disclosure: Nagesh Jadhav declares no relevant financial relationships with ineligible companies.

References

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    1. Di Nardo G, Oliva S, Aloi M, Ferrari F, Frediani S, Marcheggiano A, Cucchiara S. A pediatric non-protein losing Menetrier's disease successfully treated with octreotide long acting release. World J Gastroenterol. 2012 Jun 07;18(21):2727-9. - PMC - PubMed
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    1. Fretzayas A, Moustaki M, Alexopoulou E, Nicolaidou P. Menetrier's disease associated with Helicobacter pylori: three cases with sonographic findings and a literature review. Ann Trop Paediatr. 2011;31(2):141-7. - PubMed

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