Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Progestins

Michael Edwards  1 , Ahmet S. Can  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Progestins

Michael Edwards et al.
Free Books & Documents

Excerpt

Progestins, synthetic compounds emulating the action of progesterone, serve a pivotal role in various medical applications, spanning from contraception to postmenopausal hormone replacement therapy. These medications interact with progesterone receptors, exhibiting distinct effects based on their generational classification or structural composition. This comprehensive review delves into the mechanism of action, indications, contraindications, and potential adverse events associated with progestin therapy. Aimed at healthcare professionals involved in patient care, this activity elucidates critical facets of progestin usage, ensuring a comprehensive understanding to enable effective management of various conditions where progestins may offer therapeutic benefits.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Michael Edwards declares no relevant financial relationships with ineligible companies.

Disclosure: Ahmet Can declares no relevant financial relationships with ineligible companies.

References

    1. Selmi C, La Marca A. Oral hormonal therapy as treatment option for abnormal uterine bleeding. Eur J Contracept Reprod Health Care. 2023 Dec;28(6):285-294. - PubMed
    1. Gan JW, Lv DX, Fu J, Shi LY, Yuan CY, Zeng XQ, Li J, Sun AJ. Effectiveness of Zhenqi Buxue Oral Liquid Combined with Progesterone for Treatment of Oligomenorrhea and Hypomenorrhea with Qi-Blood and Kidney (Shen) Essence Deficiency: A Randomized Controlled Trial. Chin J Integr Med. 2023 Nov;29(11):963-970. - PubMed
    1. Dothard MI, Allard SM, Gilbert JA. The effects of hormone replacement therapy on the microbiomes of postmenopausal women. Climacteric. 2023 Jun;26(3):182-192. - PubMed
    1. Aversa T, Corica D, Pepe G, Pajno GB, Valenzise M, Messina MF, Wasniewska M. Pubertal induction in girls with Turner Syndrome. Minerva Endocrinol (Torino) 2021 Dec;46(4):469-480. - PubMed
    1. Coomarasamy A, Devall AJ, Cheed V, Harb H, Middleton LJ, Gallos ID, Williams H, Eapen AK, Roberts T, Ogwulu CC, Goranitis I, Daniels JP, Ahmed A, Bender-Atik R, Bhatia K, Bottomley C, Brewin J, Choudhary M, Crosfill F, Deb S, Duncan WC, Ewer A, Hinshaw K, Holland T, Izzat F, Johns J, Kriedt K, Lumsden MA, Manda P, Norman JE, Nunes N, Overton CE, Quenby S, Rao S, Ross J, Shahid A, Underwood M, Vaithilingam N, Watkins L, Wykes C, Horne A, Jurkovic D. A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy. N Engl J Med. 2019 May 09;380(19):1815-1824. - PubMed

Publication types

LinkOut - more resources