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Review
. 2019 Nov-Dec;22(6):510-515.
doi: 10.4103/JCD.JCD_76_20. Epub 2020 Aug 20.

Evaluation of Success Rate of Lesion Sterilization and Tissue Repair Compared to Vitapex in Pulpally Involved Primary Teeth: A Systematic Review

Smital R Agarwal  1 , Vikas D Bendgude  1 , Pradnya Kakodkar  2
Affiliations
Review

Evaluation of Success Rate of Lesion Sterilization and Tissue Repair Compared to Vitapex in Pulpally Involved Primary Teeth: A Systematic Review

Smital R Agarwal et al. J Conserv Dent. 2019 Nov-Dec.

Abstract

Background: Vitapex has been a popular obturating material for several decades. In recent times, lesion sterilization and tissue repair (LSTR) has shown promising results. This technique uses a mixture of 3 antibiotics for sterilization of the root canals and healing of periradicular tissues.

Objective: The objective of this systematic review was to compile all the literature comparing Vitapex and LSTR for pulpally involved primary teeth and evaluate the success rate in terms of clinical and radiographic outcomes.

Materials and methods: This review is based on PRISMA guidelines. The electronic search on MEDLINE via PubMed database and Google scholar, cross-referencing and hand search of journals was carried out for articles from January 1, 2000 to December 31, 2019. Articles only in the English language were selected. Out of the 17 articles, 3 unique articles were identified for the review, of which 2 were randomized controlled trials and 1 was a retrospective study.

Results: All the three articles were assessed for their quality and all had a low risk of bias. It was found that LSTR and Vitapex had a high clinical success after 12 months. The radiographic success after 6 months was high but decreased after 12 months in both the groups.

Conclusion: There is no difference in the success rate of LSTR as compared to Vitapex for the treatment of pulpally involved primary teeth.

Keywords: 3Mix paste; Vitapex; lesion sterilization and tissue repair; primary molars; pulpectomy; triple antibiotic paste.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
PRISMA study strategy flowcart
Figure 2
Figure 2
Risk of bias assessment for randomised controlled trials
Figure 3
Figure 3
Risk of bias assessment for non-randomised controlled trials
See this image and copyright information in PMC

References

    1. Rifkin A. A simple, effective, safe technique for the root canal treatment of abscessed primary teeth. ASDC J Dent Child. 1980;47:435–41. - PubMed
    1. Kubota K, Golden BE, Penugonda B. Rc filling materials for primary teeth: A review pf literature. J Dent Child. 1992;59:225–7. - PubMed
    1. Finn SB. Clinical Pedodontics. 4th ed. Philadelphia: WB Saunders Company; 1995.
    1. Fuks AB. Pulp therapy for the primary and young permanent dentition. Dent Clin North Am. 2000;44:571–96. - PubMed
    1. Holan G, Fuks AB. A comparison of pulpectomies using ZOE and KRI paste in primary molars: A retrospective study. Pediatr Dent. 1993;15:403–7. - PubMed