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Review
. 2021 Feb;70(2):158-160.
doi: 10.1007/s00101-020-00850-2.

[Cannabinoid hyperemesis as a differential diagnosis of nausea and vomiting in the emergency department]

[Article in German]
Affiliations
Review

[Cannabinoid hyperemesis as a differential diagnosis of nausea and vomiting in the emergency department]

[Article in German]
F Korn et al. Anaesthesist. 2021 Feb.

Abstract

Cannabinoid hyperemesis syndrome (CHS) is caused by regular cannabis consumption and marked by cyclic episodes of severe emesis, often years after the beginning of cannabis consumption. Classical antiemetic treatment often shows no effect and fatal outcomes have sometimes also been reported. This article describe the case of a young man in whom the diagnosis was made after four presentations due to the typical anamnesis. At this point in time he had already undergone an abdominal computed tomography (CT) and gastroscopy, both with no pathological findings. The symptoms completely receded 6 months after presentation by maintaining cannabis abstinence.

Das Cannabinoid-Hyperemesis-Syndrom (CHS) ist ein durch regelmäßigen Cannabiskonsum verursachtes Krankheitsbild, dass durch zyklische Episoden von starkem Erbrechen gekennzeichnet ist. Klassische Antiemetika bringen oft keine Linderung, teilweise wurden auch letale Verläufe beschrieben. In dem Fall eines jungen Mannes konnte nach 4 Vorstellungen die Diagnose gestellt werden. Zu diesem Zeitpunkt hatte der Patient bereits eine Abdomen-CT sowie eine Gastroskopie erhalten. Bei eingehaltener Cannabiskarenz zeigte sich 6 Monate nach Vorstellung ein kompletter Rückgang der Symptomatik.

Keywords: Cannabis abuse; Cyclic vomiting; Drugs; Therapy resistent vomiting; Unclear vomiting.

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References

    1. Albert K, Sivilotti MLA, Gareri J, et al. Hair cannabinoid concentrations in emergency patients with cannabis hyperemesis syndrome. Can J Emerg Med. 2019;21:477–481. doi: 10.1017/cem.2018.479. - DOI - PubMed
    1. Habboushe J, Rubin A, Liu H, Hoffman RS. The prevalence of cannabinoid hyperemesis syndrome among regular marijuana smokers in an urban public hospital. Basic & Clinical Pharmacology & Toxicology. 2018 doi: 10.1111/bcpt.12962. - DOI - PubMed
    1. Hasenoehrl C, Taschler U, Storr M, Schicho R. The gastrointestinal tract—a central organ of cannabinoid signaling in health and disease. Neurogastroenterol. Motil. 2017;28:1765–1780. doi: 10.1111/nmo.12931. - DOI - PMC - PubMed
    1. Kim HS, Anderson JD, Saghafi O, Heard KJ, Monte AA. Cyclic Vomiting Presentations Following Marijuana Liberalization in Colorado. Acad Emerg Med. 2015;22:694–699. doi: 10.1111/acem.12655.Cyclic. - DOI - PMC - PubMed
    1. Lacopetti C, Packer CD. Cannabinoid Hyperemesis Syndrome: a case report and review of pathophysiology. Clin Med Res. 2014;12:65–67. doi: 10.3121/cmr.2013.1179. - DOI - PMC - PubMed