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. 2020 Oct;24(19):10239-10246.
doi: 10.26355/eurrev_202010_23248.

Oxygen therapy strategies and techniques to treat hypoxia in COVID-19 patients

B Jiang  1 , H Wei
Affiliations

Oxygen therapy strategies and techniques to treat hypoxia in COVID-19 patients

B Jiang et al. Eur Rev Med Pharmacol Sci. 2020 Oct.

Abstract

Hypoxia is one of the primary causes that leads to multiple organ injuries and death in COVID-19 patients. Aggressive oxygen therapy for the treatment of hypoxia is important in saving these patients. We have summarized the mechanisms, efficacy, and side effects of various oxygen therapy techniques and their status or the potential to treat hypoxia in COVID-19 patients. The benefit to risk ratio of each oxygen therapy technique and strategy to use them in COVID-19 patients are discussed. High flow nasal cannula oxygen (HFNO) should be considered a better choice as an early stage oxygen therapy. Supraglottic jet oxygenation and ventilation (SJOV) is a promising alternative for HFNO with potential benefits.

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Conflict of interest statement

Conflict of Interest

The Authors declare that they have no conflict of interests. Huafeng Wei is the inventor of WEI Nasal Jet Tube (WEI NASAL JET, WNJ) to perform supraglottic jet oxygenation and ventilation (SJOV), and a consultant of Well Lead Medical Company, Guangzhou, China. Well Lead Medical Company has licensed WNJ from the University of Pennsylvania Trustee.

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