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Randomized Controlled Trial
. 2020;37(2):192-202.
doi: 10.36141/svdld.v37i2.9433. Epub 2020 Jun 30.

The effect of the walk-bike on quality of life and exercise capacity in patients with idiopathic pulmonary fibrosis: a feasibility study

Monique Wapenaar  1 , Elisabeth Bendstrup  2 , Maria Molina-Molina  3 , Maarten K N Stessel  4 , Jasmina Huremovic  4 , Eric W Bakker  5 , Isabella Kardys  6 , Joachim G J V Aerts  1 , Marlies S Wijsenbeek  1
Affiliations
Randomized Controlled Trial

The effect of the walk-bike on quality of life and exercise capacity in patients with idiopathic pulmonary fibrosis: a feasibility study

Monique Wapenaar et al. Sarcoidosis Vasc Diffuse Lung Dis. 2020.

Abstract

Idiopathic pulmonary fibrosis (IPF) is characterized by progressive loss of pulmonary function and exercise capacity, leading to loss of quality of life and often social isolation. A new walking aid, the walk-bike, showed an improvement in exercise performance in COPD patients. Aims of this pilot study were to evaluate feasibility of a homebased walk-bike intervention study in IPF patients and to explore the effect of the walk-bike on quality of life (QoL) and exercise capacity. Twenty-three patients with IPF were included in a randomized multicenter crossover study with 8 weeks of standard care and 8 weeks of walk-bike use at home. Ten patients completed both study phases. Study barriers included reluctance to participate and external factors (e.g. weather and road conditions) that hampered adherence. Patients' satisfaction and experience with the walk-bike varied greatly. After training with the walk-bike, health-related QoL (St. George's Respiratory and King's Brief Interstitial Lung Disease questionnaires) demonstrated a tendency towards improvement, exercise capacity did not. A clinically important difference was found between 6-minute walk test with the walk-bike and the standard test; median (range) respectively 602 m (358-684) and 486 m (382-510). Conclusions: Due to practical barriers a larger study with the walk-bike in patients with IPF seems not feasible. Individual patients may benefit from the use of a walk-bike as it improved action radius and showed a tendency towards improvement in QoL. No effect on exercise capacity was observed. (Sarcoidosis Vasc Diffuse Lung Dis 2020; 37 (2): 192-202).

Keywords: Exercise capacity; Exercise training; Home-based training; Idiopathic Pulmonary Fibrosis; Quality of Life.

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Figures

Fig. 1.
Fig. 1.
Walk-bike
Fig. 2.
Fig. 2.
Study flow chart of patients screened and enrolled
Fig. 3.
Fig. 3.
Individual changes in SGRQ- and K-BILD total scores during control and intervention period. A negative change in SGRQ score indicates an improvement in health-related quality of life, a positive change in K-BILD score indicates an improvement in health-related quality of life
Fig. 4.
Fig. 4.
Individual differences in 6MWD and lowest SpO2 during 6MWT with and without walk-bike
See this image and copyright information in PMC

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