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Meta-Analysis
. 2020 Oct 23;15(10):e0241265.
doi: 10.1371/journal.pone.0241265. eCollection 2020.

Prevalence of underlying diseases in died cases of COVID-19: A systematic review and meta-analysis

Fatemeh Javanmardi  1 , Abdolkhalegh Keshavarzi  2 , Ali Akbari  3 , Amir Emami  1 , Neda Pirbonyeh  1
Affiliations
Meta-Analysis

Prevalence of underlying diseases in died cases of COVID-19: A systematic review and meta-analysis

Fatemeh Javanmardi et al. PLoS One. .

Abstract

Introduction: Underlying disease have a critical role in vulnerability of populations for a greater morbidity and mortality when they suffer from COVID-19. The aim of current study is evaluating the prevalence of underlying disease in died people with COVID-19.

Methods: The current study have been conducted according to PRISMA guideline. International database including PubMed, Scopus, Web of Science, Cochrane and google scholar were searched for relevant studies up to 1 June. All relevant articles that reported underlying disease in died cases of COVID-19 were included in the analysis.

Results: After screening and excluding duplicated and irrelevant studies, 32 articles included in the analysis. The most prevalent comorbidities were hypertension, diabetes, cardiovascular disease, liver disease, lung disease, malignancy, cerebrovascular disease, COPD and asthma. Among all reported underlying disease, highest and lowest prevalence was related to hypertension and asthma which were estimated 46% (37% - 55%) and 3% (2%- 6%), respectively.

Conclusion: In summary, underlying disease have a critical role in poor outcomes, severity of disease and high mortality rate of COVID-19 cases. Patients with hypertension, cardiovascular disease and diabetes should be carefully monitored and be aware of health protocols.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. PRISMA flow chart of the systematic literature review and article identification.
Fig 2
Fig 2. Prevalence of hypertension among died patients with COVID-19.
Fig 3
Fig 3. Prevalence of diabetes among died patients with COVID-19.
Fig 4
Fig 4. Prevalence of cardiovascular disease among died patients with COVID-19.
Fig 5
Fig 5. Prevalence of kidney disease among died patients with COVID-19.
Fig 6
Fig 6. Prevalence of COPD among died patients with COVID-19.
Fig 7
Fig 7. Prevalence of malignancy among died patients with COVID-19.
Fig 8
Fig 8. Prevalence of malignancy among died patients with COVID-19.
Fig 9
Fig 9. Prevalence of lung disease among died patients with COVID-19.
Fig 10
Fig 10. Prevalence of cerebrovascular disease among died patients with COVID-19.
See this image and copyright information in PMC

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