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Editorial
. 2020 Nov;22(7):657-659.
doi: 10.1111/bdi.13026.

In vivo phenotyping, mechanism-informed treatments, domain-based psychopathology and nomological networks: A strategy for treatment discovery and development in bipolar depression

Roger S McIntyre  1
Affiliations
Editorial

In vivo phenotyping, mechanism-informed treatments, domain-based psychopathology and nomological networks: A strategy for treatment discovery and development in bipolar depression

Roger S McIntyre. Bipolar Disord. 2020 Nov.
No abstract available

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References

REFERENCES

    1. McIntyre RS, Calabrese JR. Bipolar depression: the clinical characteristics and unmet needs of a complex disorder. Curr Med Res Opin. 2019;35(11):1993-2005.
    1. Rhee TG, Olfson M, Nierenberg AA, Wilkinson ST. 20-Year Trends in the pharmacologic treatment of bipolar disorder by psychiatrists in outpatient care settings. Am J Psychiatry. 2020;177(8):706-715.
    1. Krystal AD, Pizzagalli DA, Smoski M, et al. A randomized proof-of-mechanism trial applying the “fast-fail” approach to evaluating κ-opioid antagonism as a treatment for anhedonia. Nat Med. 2020;26(5):760-768.
    1. McIntyre RS, Subramaniapillai M, Lee Y, et al. Efficacy of Adjunctive Infliximab vs Placebo in the Treatment of Adults With Bipolar I/II Depression: A Randomized Clinical Trial . JAMA Psychiatry. 2019;76(8):783. https://doi.org/10.1001/jamapsychiatry.2019.0779.
    1. McIntyre RS, Berk M, Brietzke E, et al. Bipolar disorders. Lancet. [In-press. 2020;396.

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