Reissuing the sigma receptors for SARS-CoV-2
- PMID: 33099370
- PMCID: PMC7418634
- DOI: 10.1016/j.jocn.2020.08.014
Reissuing the sigma receptors for SARS-CoV-2
Abstract
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Receptor binding is a major determinant of tissue tropism for SARS-CoV-2.
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Neurotropism of SARS-CoV-2 associated with a broad range of receptors in the central nervous system (CNS).
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Sigma receptors may be involved in the neuronal transmission of SARS-CoV-2.
Keywords: Antiviral agents; Brain; COVID-19; Coronavirus pandemic; SARS-CoV-2; Sigma receptors.
Conflict of interest statement
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Comment on
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How SARS-Cov-2 can involve the central nervous system. A systematic analysis of literature of the department of human neurosciences of Sapienza University, Italy.J Clin Neurosci. 2020 Sep;79:231-236. doi: 10.1016/j.jocn.2020.07.007. Epub 2020 Jul 7. J Clin Neurosci. 2020. PMID: 33070902 Free PMC article. Review.
References
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- Armocida D., Palmieri M., Frati A., Santoro A., Pesce A. How SARS-Cov-2 can involve the central nervous system. A systematic analysis of literature of the department of human neurosciences of Sapienza university, Italy. J Clin Neurosci. 2020;79:231–236. doi: 10.1016/j.jocn.2020.07.007. - DOI - PMC - PubMed
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