Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Nov;104(6):1063-1078.
doi: 10.1016/j.mcna.2020.08.006.

Screening for Cervical Cancer

Affiliations
Review

Screening for Cervical Cancer

Terresa J Eun et al. Med Clin North Am. 2020 Nov.

Abstract

The most effective strategy for cervical cancer prevention involves vaccination to prevent human papillomavirus (HPV) infections during adolescence followed by screening to detect HPV infections during adulthood. HPV vaccination before sexual debut can prevent HPV infections, precancers, and cancers. HPV vaccination of sexually active populations does not prevent cancer. Screening with HPV testing is the most effective method of detecting precancers and cancers between ages 25 and 65. Ensuring adequate screening around the age of menopause may be the key to preventing cervical cancer among elderly women. Most cervical cancers at all ages occur among unscreened or underscreened women.

Keywords: Cervical cancer screening; Cervical cytology; HPV test; PAP test.

PubMed Disclaimer

Conflict of interest statement

Disclosure No disclosures.

References

    1. SEER. Available at: http://seer.cancer.gov/statfacts/html/cervix.html#incidence-mortality. Accessed April 21, 2020.
    1. Schiffman M, Wentzensen N, Wacholder S, et al. Human papillomavirus testing in the prevention of cervical cancer. J Natl Cancer Inst 2011;103(5):368–83. - PMC - PubMed
    1. Clifford G, Franceschi S, Diaz M, et al. Chapter 3: HPV type-distribution in women with and without cervical neoplastic diseases. Vaccine 2006;24(Suppl 3):S26–34. - PubMed
    1. Schiffman MH, Brinton LA. The epidemiology of cervical carcinogenesis. Cancer 1995;76(10 Suppl):1888–901. - PubMed
    1. Demarco M, Egemen D, Raine-Bennett TR, et al. A study of partial human papillomavirus genotyping in support of the 2019 ASCCP risk-based management consensus guidelines. J Low Genit Tract Dis 2020;24(2):144–7. - PMC - PubMed