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Editorial
. 2021 Jan;21(1):9-10.
doi: 10.1111/ajt.16376. Epub 2020 Nov 18.

Understanding the impact of HLA molecular mismatch in solid organ transplantation: Are we there yet?

Annette M Jackson  1 , David F Pinelli  2
Affiliations
Free article
Editorial

Understanding the impact of HLA molecular mismatch in solid organ transplantation: Are we there yet?

Annette M Jackson et al. Am J Transplant. 2021 Jan.
Free article
No abstract available

Keywords: antigen biology; editorial / personal viewpoint; histocompatibility; immunosuppressant; organ transplantation in general.

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References

REFERENCES

    1. Wiebe C, Kosmoliaptsis V, Pochinco D, Taylor CJ, Nickerson P. A Comparison of HLA Molecular Mismatch Methods to Determine HLA Immunogenicity. Transplantation. 2018;102(8):1338-1343.
    1. Engen RM, Jedraszko AM, Conciatori MA, Tambur AR. Substituting imputation of HLA antigens for high-resolution HLA typing: Evaluation of a multiethnic population and implications for clinical decision making in transplantation. Am J Transplant. 2020. in press.
    1. Nédélec Y, Sanz J, Baharian G, et al. Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens. Cell. 2016;167(3):657-669 e21.
    1. Reindl-Schwaighofer R, Heinzel A, Signorini L, Thaunat O, Oberbauer R. Mechanisms underlying human genetic diversity: consequence for antigraft antibody responses. Transpl Int. 2018;31(3):239-250.
    1. Davis S, Wiebe C, Campbell K, et al. Adequate Tacrolimus Exposure Modulates the Impact of HLA Class II Molecular Mismatch: A Validation Study in an American Cohort. Am J Transplant. 2020. in press.