Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 May;93(5):2810-2814.
doi: 10.1002/jmv.26633. Epub 2021 Feb 23.

Fungemia in COVID-19 ICU patients, a single medical center experience

Eliahu Bishburg  1 , Alexis Okoh  1 , Sandhya R Nagarakanti  1 , Marc Lindner  1 , Christina Migliore  1 , Pratik Patel  1
Affiliations

Fungemia in COVID-19 ICU patients, a single medical center experience

Eliahu Bishburg et al. J Med Virol. 2021 May.

Abstract

A known proportion of patients who are admitted for the novel coronavirus disease 2019 (COVID-19) requires intensive care unit (ICU) level of care. Prolonged ICU stay is a risk factor for the development of nosocomial candidemia. The current study aimed to investigate the incidence and risk factors associated with the development of nosocomial candidemia among patients admitted to the ICU for COVID-19. Patients who developed nosocomial candidemia were identified, and their clinical course was reported. A 1:3 case control matching was used to identify non-candidemia patients who served as controls. 89 patients were admitted to the ICU for COVID-19 during the study period. The incidence of nosocomial candidemia was 8.9% (n = 8). Case-control matching identified 24 patients with similar disease severity at the time of ICU admission. Median time to first isolation of yeast was 26 days. Candidemia patients reported longer median ICU stay than controls. (40 vs. 10 days, p = .004). In hospital death rates were comparable in both groups (38% vs. 54%, p = .548). Prolonged mechanical ventilation support was associated with the development of nosocomial candidemia.

PubMed Disclaimer

References

REFERENCES

    1. The World Health Organization (2020) Coronavirus disease (COVID-19) pandemic. https://who.int/emergencies/diseases/novel-coronavirus-2019
    1. Wu Z, McGoogan JM. Charachteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020;323(13):1239-1242.
    1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan China. Lancet. 2020;395(102223):497-506.
    1. Grasselli G, Zangrillo A, Zanella A, et al. Baseline charachteristics and outcomes of 1591 patients infected with SARS- CoV-2 admitted to ICUs of the Lombardy region, Italy. JAMA. 2020;323(16):1574-1581.
    1. Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective Nationwide Surveillance Study. CID. 2004;39:309-317.

LinkOut - more resources