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. 2020 Oct 26;55(2):111-113.
doi: 10.1016/j.devcel.2020.09.027.

Breaking Bad: Extracellular Vesicles Provoke Tumorigenic Responses Under Oxygen Deprivation

Alex C Boomgarden  1 , James W Clancy  1 , Crislyn D'Souza-Schorey  2
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Breaking Bad: Extracellular Vesicles Provoke Tumorigenic Responses Under Oxygen Deprivation

Alex C Boomgarden et al. Dev Cell. .
Free article

Abstract

Intercellular communication is vital to tumor progression. In this issue of Developmental Cell, Bertolini et al. (2020) describe how small extracellular vesicles released from hypoxic mammary tumor cells facilitate intercellular communication, leading to alterations in mitochondrial dynamics and acquisition of invasive phenotypes in normal epithelial cells.

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