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Comment
. 2020 Oct 26;55(2):113-115.
doi: 10.1016/j.devcel.2020.10.001.

MTORC1 and the Rebirth of Stemness

Nicolette M Johnson  1 , Christopher J Lengner  2
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MTORC1 and the Rebirth of Stemness

Nicolette M Johnson et al. Dev Cell. .
Free article

Abstract

MTORC1 activity is critical for tissue regeneration in multiple organs and contexts. In this issue of Developmental Cell, Miao et al. describe upstream regulators of mTORC1 activity which promote paligenosis, a process where mature cells de-differentiate to acquire stem cell activity in the face of injury.

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