Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Nov;33(6):e14470.
doi: 10.1111/dth.14470. Epub 2020 Nov 16.

Refractory ulcerations associated with livedoid vasculopathy successfully treated with tofacitinib

Ertao Jia  1 , Guangyao Yan  1 , Min Xiao  1 , Hongling Geng  2 , Jiaxin Wei  1 , Jianyong Zhang  1
Affiliations
Case Reports

Refractory ulcerations associated with livedoid vasculopathy successfully treated with tofacitinib

Ertao Jia et al. Dermatol Ther. 2020 Nov.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Purpuric macules and livedo racemosa on the dorsal feet and the lower legs before treatment
FIGURE 2
FIGURE 2
Pathology of skin tissue biopsy, skin biopsy revealed infiltration of lymphocytes around small blood vessels in the dermis, vascular wall fibrinoid deposition and vascular lumen fibrinoid thrombosis (hematoxylin and eosin, original magnification ×100)
FIGURE 3
FIGURE 3
The ulcer improved remarkably after 1 month of treatment
See this image and copyright information in PMC

References

    1. Kumar A, Sharma A, Agarwal A. Livedoid vasculopathy presenting with leg ulcers. Rheumatology (Oxford). 2019;58(11):2076. - PubMed
    1. Gardette E, Moguelet P, Bouaziz JD, et al. Livedoid vasculopathy: a French observational study including therapeutic options. Acta Derm Venereol. 2018;98(9):842‐847. - PubMed
    1. Kelly RI, Wee E, Tancharoen C, Tam MM, Balta S, Williams RA. Three cases of lymphocytic thrombophilic arteritis presenting with an annular eruption. Australas J Dermatol. 2018;59(2):e127‐e132. - PubMed
    1. Irani‐Hakime NA, Stephan F, Kreidy R, Jureidini I, Almawi WY. Livedoid vasculopathy associated with combined prothrombin G20210A and factor V (Leiden) heterozygosity and MTHFR C677T homozygosity. J Thromb Thrombolysis. 2008;26(1):31‐34. - PubMed
    1. Gao Y, Jin H. Efficacy of an anti‐TNF‐alpha agent in refractory livedoid vasculopathy: a retrospective analysis. Dermatol Treat. 2020;1‐6. - PubMed