Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2020 Oct 26;9(11):734.
doi: 10.3390/antibiotics9110734.

Phage Diversity for Research and Application

Christine Rohde  1 , Johannes Wittmann  1
Affiliations
Editorial

Phage Diversity for Research and Application

Christine Rohde et al. Antibiotics (Basel). .

Abstract

Bacteriophages (in short, phages) are viruses that specifically recognize and infect bacteria; theyare the most abundant forms of life in the biosphere outnumbering bacteria by an estimated factor ofone order of magnitude [1]. Logically, lytic phages have an enormous potential in human andveterinary medicine as "intelligent antibiotics". In contrast to static antibacterial drugs, phagesself-control their numbers at the locus of bacterial infection as they replicate on the unwantedpathogen and disintegrate into their subunits when the bacterial host is eliminated. [...].

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Cobian Guemes A.G., Youle M., Cantu V.A., Felts B., Nulton J., Rohwer F. Viruses as Winners in the Game of Life. Annu. Rev. Virol. 2016;3:197–214. doi: 10.1146/annurev-virology-100114-054952. - DOI - PubMed
    1. Kittler S., Wittmann J., Mengden R.A.L.P., Klein G., Rohde C., Lehnherr H. The use of bacteriophages as One-Health approach to reduce multidrug-resistant bacteria. Sustain. Chem. Pharm. 2017;5:80–83. doi: 10.1016/j.scp.2016.06.001. - DOI
    1. Erez Z., Steinberger-Levy I., Shamir M., Doron S., Stokar-Avihail A., Peleg Y., Melamed S., Leavitt A., Savidor A., Albeck S., et al. Communication between viruses guides lysis-lysogeny decisions. Nature. 2017;541:488–493. doi: 10.1038/nature21049. - DOI - PMC - PubMed
    1. Hayes S., Mahony J., Nauta A., van Sinderen D. Metagenomic Approaches to Assess Bacteriophages in Various Environmental Niches. Viruses. 2017;9:127. doi: 10.3390/v9060127. - DOI - PMC - PubMed
    1. Eisenman D.J. Rereading Arrowsmith in the COVID-19 Pandemic. JAMA. 2020;324:319–320. doi: 10.1001/jama.2020.11489. - DOI - PubMed

Publication types

LinkOut - more resources