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. 2020 Dec;10(12):OF2.
doi: 10.1158/2159-8290.CD-NB2020-098. Epub 2020 Oct 28.

Another KRAS Inhibitor Holds Its Own

No authors listed

Another KRAS Inhibitor Holds Its Own

No authors listed. Cancer Discov. 2020 Dec.

Abstract

According to the KRYSTAL-1 study, the KRASG12c inhibitor adagrasib, also known as MRTX849, is largely well tolerated and shows considerable efficacy in patients with non-small cell lung cancer harboring this mutation. The drug is also active, albeit more modestly, in colorectal cancer and several other solid tumor types.

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