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Clinical Trial
. 1987 Oct;28(2):161-9.
doi: 10.1016/0090-8258(87)90210-1.

A randomized study of cyclophosphamide and cis-platinum with or without doxorubicin in advanced ovarian carcinoma

K Bertelsen  1 , A Jakobsen, J E Andersen, S Ahrons, P H Pedersen, H Kiaer, E Arffmann, P Bichel, E Boestofte, I Strøyer, et al.
Affiliations
Clinical Trial

A randomized study of cyclophosphamide and cis-platinum with or without doxorubicin in advanced ovarian carcinoma

K Bertelsen et al. Gynecol Oncol. 1987 Oct.

Abstract

Two hundred sixty-seven patients with advanced epithelial ovarian carcinoma were randomized to cis-platinum and cyclophosphamide versus cis-platinum, cyclophosphamide, and doxorubicin. Complete pathological response, evaluated at second-look laparotomy and survival, showed no differences between the two treatment groups. Recurrence-free survival after negative second look was 61% at 24 months.

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