Competing interests: L. Palaniyappan reports personal fees from Janssen Canada, Otsuka Canada, SPMM Course Limited, UK, and the Canadian Psychiatric Association; book royalties from Oxford University Press; investigator-initiated educational grants from Sunovion, Janssen Canada, and Otsuka Canada; and travel support from Boehringer Ingelheim and Magstim Limited, outside the submitted work. He is a member of the JPN editorial board, but was not involved in the review or the decision to accept this manuscript for publication. No other competing interests were declared.