Frailty and mortality in patients with COVID-19

Affiliations

¹ Department of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC 3050, Australia; Centre for Integrated Critical Care, The University of Melbourne, Melbourne, VIC, Australia. Electronic address: jai.darvall@mh.org.au.
² Department of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC 3050, Australia; Centre for Integrated Critical Care, The University of Melbourne, Melbourne, VIC, Australia; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Data Analytics Research & Evaluation Centre, The University of Melbourne and Austin Hospital, Melbourne, VIC, Australia.
³ Medical Research Institute of New Zealand, Wellington, New Zealand.
⁴ Divisions of Geriatric Medicine & Neurology, and the Geriatric Medicine Research Unit, Division of Geriatric Medicine, Department of Medicine, Dalhousie University and Nova Scotia Health Authority, Nova Scotia, Canada.
⁵ Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Intensive Care, Alfred Hospital, Melbourne, VIC, Australia; Centre for Outcome and Resource Evaluation, Australian and New Zealand Intensive Care Society, Melbourne, VIC, Australia.

Comment

Jai N Darvall et al. Lancet Public Health. 2020 Nov.

. 2020 Nov;5(11):e580.

doi: 10.1016/S2468-2667(20)30228-0.

¹ Department of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC 3050, Australia; Centre for Integrated Critical Care, The University of Melbourne, Melbourne, VIC, Australia. Electronic address: jai.darvall@mh.org.au.
² Department of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC 3050, Australia; Centre for Integrated Critical Care, The University of Melbourne, Melbourne, VIC, Australia; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Data Analytics Research & Evaluation Centre, The University of Melbourne and Austin Hospital, Melbourne, VIC, Australia.
³ Medical Research Institute of New Zealand, Wellington, New Zealand.
⁴ Divisions of Geriatric Medicine & Neurology, and the Geriatric Medicine Research Unit, Division of Geriatric Medicine, Department of Medicine, Dalhousie University and Nova Scotia Health Authority, Nova Scotia, Canada.
⁵ Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Intensive Care, Alfred Hospital, Melbourne, VIC, Australia; Centre for Outcome and Resource Evaluation, Australian and New Zealand Intensive Care Society, Melbourne, VIC, Australia.

No abstract available

Comment in

Frailty and mortality in patients with COVID-19.
Pan D, Sze S, Minhas JS, Squire IB, Pareek M. Pan D, et al. Lancet Public Health. 2020 Nov;5(11):e581. doi: 10.1016/S2468-2667(20)30229-2. Lancet Public Health. 2020. PMID: 33120042 Free PMC article. No abstract available.
Frailty and mortality in patients with COVID-19 - Authors' reply.
McCarthy K, Hewitt J, Myint PK, Quinn T, Carter B. McCarthy K, et al. Lancet Public Health. 2020 Nov;5(11):e582. doi: 10.1016/S2468-2667(20)30224-3. Lancet Public Health. 2020. PMID: 33120043 Free PMC article. No abstract available.

The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study.
Hewitt J, Carter B, Vilches-Moraga A, Quinn TJ, Braude P, Verduri A, Pearce L, Stechman M, Short R, Price A, Collins JT, Bruce E, Einarsson A, Rickard F, Mitchell E, Holloway M, Hesford J, Barlow-Pay F, Clini E, Myint PK, Moug SJ, McCarthy K; COPE Study Collaborators. Hewitt J, et al. Lancet Public Health. 2020 Aug;5(8):e444-e451. doi: 10.1016/S2468-2667(20)30146-8. Epub 2020 Jun 30. Lancet Public Health. 2020. PMID: 32619408 Free PMC article.
Frailty and mortality in patients with COVID-19.
Laurent MR. Laurent MR. Lancet Public Health. 2020 Nov;5(11):e579. doi: 10.1016/S2468-2667(20)30227-9. Lancet Public Health. 2020. PMID: 33120040 Free PMC article. No abstract available.

1. Hewitt J, Carter B, Vilches-Moraga A. The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study. Lancet Public Health. 2020;5:e444–e451. - PMC - PubMed
1. National Institute for Health and Care Excellence COVID-19 rapid guideline: critical care in adults. NICE guideline [NG159] March 20, 2020. https://www.nice.org.uk/guidance/ng159 - PubMed
1. Darvall JN, Bellomo R, Paul E. Frailty in very old critically ill patients in Australia and New Zealand: a population-based cohort study. Med J Aust. 2019;211:318–323. - PubMed
1. Intensive care national audit & research centre ICNARC report on COVID-19 in critical care. June 19, 2020. https://www.icnarc.org/DataServices/Attachments/Download/da19fd54-70b2-e...
1. Rockwood K, Song X, MacKnight C. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005;173:489–495. - PMC - PubMed