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Review
. 2020 Dec;40(4):433-446.
doi: 10.1016/j.cll.2020.08.002. Epub 2020 Sep 30.

Update on Susceptibility Testing: Genotypic and Phenotypic Methods

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Review

Update on Susceptibility Testing: Genotypic and Phenotypic Methods

Romney M Humphries. Clin Lab Med. 2020 Dec.

Abstract

Antimicrobial susceptibility testing (AST) is now, more than ever, a critical role of the microbiology laboratory. Several factors limit its application for patient care and antimicrobial resistance epidemiology, including time to results, requirements for pure cultures, and high starting concentration of bacteria. This review discusses the global status of AST and new phenotypic and genotypic methods in late-stage development or that are new to market.

Keywords: Antimicrobial resistance; Antimicrobial susceptibility testing; Bacteriology.

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Conflict of interest statement

Disclosure R.M. Humphries is a past employee of Accelerate Diagnostics and a current shareholder.

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