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Comment
. 2021 Mar;82(3):414-451.
doi: 10.1016/j.jinf.2020.10.025. Epub 2020 Oct 27.

SARS-CoV-2 positive virus culture 7 weeks after onset of COVID-19 in an immunocompromised patient suffering from X chromosome-linked agammaglobulinemia

Katharina Guetl  1 , Florentine Moazedi-Fuerst  2 , Konrad Rosskopf  3 , Marianne Brodmann  1 , Robert Krause  4 , Philipp Eller  5 , Patricia Wilhelmer  6 , Florian Eisner  5 , Nazanin Sareban  3 , Peter Schlenke  7 , Harald H Kessler  8 , Ivo Steinmetz  8 , Monika Redlberger-Fritz  9 , Karin Stiasny  9 , Martin Stradner  10
Affiliations
Comment

SARS-CoV-2 positive virus culture 7 weeks after onset of COVID-19 in an immunocompromised patient suffering from X chromosome-linked agammaglobulinemia

Katharina Guetl et al. J Infect. 2021 Mar.
No abstract available

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Conflict of interest statement

Declaration of Competing Interest None to declare.

Figures

Fig. 1
Fig. 1
Timeline presenting milestones of disease from onset of COVID 19 up until negative virus culture. Our patient was diagnosed with COVID-19 based on a positive result from SARS-CoV-2 RT-PCR first on March 11. Admission to the hospital was required on March 27 due to progressive clinical deterioration. Administration of an experimental treatment approach comprising convalescent plasma transfusion and interleukin-6 receptor blockade by tocilizumab was performed on April 10 and convalescent plasma was administered for a second time on April 21. A virus culture within week 7 of disease still showed a positive result and, thus, confirmed prolonged viral shedding in this patient. Viral culture control in week 10 presented a negative result. COVID-19 = coronavirus disease 2019; SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2; RT-PCR = real-time polymerase chain reaction.
See this image and copyright information in PMC

Comment on

  • The duration of infectiousness of individuals infected with SARS-CoV-2.
    Walsh KA, Spillane S, Comber L, Cardwell K, Harrington P, Connell J, Teljeur C, Broderick N, de Gascun CF, Smith SM, Ryan M, O'Neill M. Walsh KA, et al. J Infect. 2020 Dec;81(6):847-856. doi: 10.1016/j.jinf.2020.10.009. Epub 2020 Oct 10. J Infect. 2020. PMID: 33049331 Free PMC article. Review.

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