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Editorial
. 2020 Nov;104(11):2246-2248.
doi: 10.1097/TP.0000000000003358.

Myeloid Cell Memory via PIR-A: A Game Changer in Allograft Rejection Cascade?

Hidenobu Kojima  1 , Jerzy W Kupiec-Weglinski
Affiliations
Editorial

Myeloid Cell Memory via PIR-A: A Game Changer in Allograft Rejection Cascade?

Hidenobu Kojima et al. Transplantation. 2020 Nov.
No abstract available

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Comment on

  • PIRs mediate innate myeloid cell memory to nonself MHC molecules.
    Dai H, Lan P, Zhao D, Abou-Daya K, Liu W, Chen W, Friday AJ, Williams AL, Sun T, Chen J, Chen W, Mortin-Toth S, Danska JS, Wiebe C, Nickerson P, Li T, Mathews LR, Turnquist HR, Nicotra ML, Gingras S, Takayama E, Kubagawa H, Shlomchik MJ, Oberbarnscheidt MH, Li XC, Lakkis FG. Dai H, et al. Science. 2020 Jun 5;368(6495):1122-1127. doi: 10.1126/science.aax4040. Epub 2020 May 7. Science. 2020. PMID: 32381589 Free PMC article.

References

    1. Netea MG, Joosten LA, Latz E, et al. Trained immunity: a program of innate immune memory in health and disease. Science. 2016; 352:aaf1098
    1. Dai H, Lan P, Zhao D, et al. PIRs mediate innate myeloid cell memory to nonself MHC molecules. Science. 2020; 368:1122–1127
    1. Meier-Kriesche HU, Schold JD, Srinivas TR, et al. Lack of improvement in renal allograft survival despite a marked decrease in acute rejection rates over the most recent era. Am J Transplant. 2004; 4:378–383
    1. Kubagawa H, Chen CC, Ho LH, et al. Biochemical nature and cellular distribution of the paired immunoglobulin-like receptors, PIR-A and PIR-B. J Exp Med. 1999; 189:309–318
    1. Endo S, Sakamoto Y, Kobayashi E, et al. Regulation of cytotoxic T lymphocyte triggering by PIR-B on dendritic cells. Proc Natl Acad Sci U S A. 2008; 105:14515–14520

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