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Review
. 2021 Jan-Feb;42(1):102795.
doi: 10.1016/j.amjoto.2020.102795. Epub 2020 Oct 24.

Structured histopathology for endotyping and planning rational treatment in chronic rhinosinusitis

Giuseppe Brescia  1 , Lara Alessandrini  2 , Gino Marioni  3
Affiliations
Review

Structured histopathology for endotyping and planning rational treatment in chronic rhinosinusitis

Giuseppe Brescia et al. Am J Otolaryngol. 2021 Jan-Feb.

Abstract

In chronic rhinosinusitis (CRS), endotyping, being based on the pathogenic mechanism, provides a precise picture appropriate for use in clinical practice. Structured histopathological examination of CRS is considered a necessary step in efforts to establish its pathogenesis and improve our endotyping capabilities. Herein we discuss the associations between histopathology and clinical characteristics of CRS patients to assist medical and surgical treatment choices.

Keywords: Biologics; Chronic rhinosinusitis; Endotypes; Nasal polyps; Structured histopathology.

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