Environmental exposures and sleep outcomes: A review of evidence, potential mechanisms, and implications

Abstract

Environmental exposures and poor sleep outcomes are known to have consequential effects on human health. This integrative review first seeks to present and synthesize existing literature investigating the relationship between exposure to various environmental factors and sleep health. We then present potential mechanisms of action as well as implications for policy and future research for each environmental exposure. Broadly, although studies are still emerging, empirical evidence has begun to show a positive association between adverse effects of heavy metal, noise pollution, light pollution, second-hand smoke, and air pollution exposures and various sleep problems. Specifically, these negative sleep outcomes range from subjective sleep manifestations, such as general sleep quality, sleep duration, daytime dysfunction, and daytime sleepiness, as well as objective sleep measures, including difficulties with sleep onset and maintenance, sleep stage or circadian rhythm interference, sleep arousal, REM activity, and sleep disordered breathing. However, the association between light exposure and sleep is less clear. Potential toxicological mechanisms are thought to include the direct effect of various environmental toxicants on the nervous, respiratory, and cardiovascular systems, oxidative stress, and inflammation. Nevertheless, future research is required to tease out the exact pathways of action to explain the associations between each environmental factor and sleep, to inform possible therapies to negate the detrimental effects, and to increase efforts in decreasing exposure to these harmful environmental factors to improve health.

Keywords: Air pollution; Environmental exposure; Heavy metals; Noise and light pollution; Second-hand smoke; Sleep.

Fig. 1.

Conceptual framework of possible mechanisms for the association between heavy metal exposure and poor sleep health.

Fig. 2.

Conceptual framework of possible mechanisms for the association between noise pollution and poor sleep health.

Fig. 3.

Conceptual framework of possible mechanisms for the association between light pollution and poor sleep health.

Fig. 4.

Conceptual framework of possible mechanisms for the association between second-hand smoke exposure and poor sleep health.

Fig. 5.

Conceptual framework of possible mechanisms for the association between air pollution exposure and poor sleep health.