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. 2020 Nov 1;105(11):2675-2678.
doi: 10.3324/haematol.2019.240564.

The role of 18F-FDG-PET in detecting Richter's transformation of chronic lymphocytic leukemia in patients receiving therapy with a B-cell receptor inhibitor

Yucai Wang  1 , Kari G Rabe  2 , Michael S Bold  3 , Min Shi  4 , Curtis A Hanson  4 , Susan M Schwager  1 , Timothy G Call  1 , Saad S Kenderian  1 , Eli Muchtar  1 , Suzanne R Hayman  1 , Amber B Koehler  1 , Amie L Fonder  1 , Asher A Chanan-Khan  5 , Daniel L Van Dyke  6 , Susan L Slager  2 , Neil E Kay  1 , Wei Ding  1 , Jose F Leis  7 , Sameer A Parikh  1
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The role of 18F-FDG-PET in detecting Richter's transformation of chronic lymphocytic leukemia in patients receiving therapy with a B-cell receptor inhibitor

Yucai Wang et al. Haematologica. .
No abstract available

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Figures

Figure 1.
Figure 1.
SUVmax on a PET scan. (A) Distribution of SUVmax by pathology. (B) Sensitivity, specificity, and positive and negative predictive values of different SUVmax thresholds in detecting Richter transformation (n=54): cROC analysis of SUVmax cut-off for identifying Richter transformation. SUV: standardized uptake value; PET: positron emission tomography.
See this image and copyright information in PMC

References

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    1. Rossi D, Gaidano G. Richter syndrome: pathogenesis and management. Semin Oncol. 2016;43(2):311-319. - PubMed
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    1. Wang Y, Tschautscher MA, Rabe KG, et al. Clinical characteristics and outcomes of Richter transformation: Experience of 204 patients from a single center. Haematologica. 2020;105(3):765-773. - PMC - PubMed
    1. Bruzzi JF, Macapinlac H, Tsimberidou AM, et al. Detection of Richter's transformation of chronic lymphocytic leukemia by PET/CT. J Nucl Med. 2006;47(8):1267-1273. - PubMed

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