Noninvasive Ventilation and Spinal Cord Injury
- PMID: 33131657
- DOI: 10.1016/j.jsmc.2020.08.006
Noninvasive Ventilation and Spinal Cord Injury
Abstract
Individuals with spinal cord injury (SCI) are at increased risk of respiratory complications during wake and sleep. Sleep-disordered breathing (SDB) is commonly associated with SCI and requires an individualized approach to its management. Respiratory control plays a key role in the pathogenesis of SDB in cervical SCI. Noninvasive ventilation plays an important role in the management of respiratory complications in individuals with SCI acutely and in chronic phases. Positive airway pressure treatment may be effective in eliminating SDB and improving sleepiness symptoms, but adherence to treatment is poor and effect on long-term outcomes is questionable.
Keywords: Noninvasive ventilation; Sleep; Sleep-disordered breathing; Spinal cord injury (SCI).
Copyright © 2020 Elsevier Inc. All rights reserved.
Conflict of interest statement
Disclosure This study was not industry supported. The authors have no financial conflicts of interest. The opinions expressed in this article reflect those of the authors and do not necessarily represent official views of Department of Veterans’ Affairs (VA). Dr A. Sankari is supported by the Office of Research and Development from the VA award RX002885 and from the National Heart, Lung, and Blood Institute awards HL140447 and HL130552.
Similar articles
-
Sleep-Disordered Breathing and Spinal Cord Injury: A State-of-the-Art Review.Chest. 2019 Feb;155(2):438-445. doi: 10.1016/j.chest.2018.10.002. Epub 2018 Oct 12. Chest. 2019. PMID: 30321507 Free PMC article. Review.
-
Sleep disordered breathing in chronic spinal cord injury.J Clin Sleep Med. 2014 Jan 15;10(1):65-72. doi: 10.5664/jcsm.3362. J Clin Sleep Med. 2014. PMID: 24426822 Free PMC article.
-
Identification and treatment of sleep-disordered breathing in chronic spinal cord injury.Spinal Cord. 2015 Feb;53(2):145-9. doi: 10.1038/sc.2014.216. Epub 2014 Dec 16. Spinal Cord. 2015. PMID: 25510191
-
Sleep disordered breathing induced by cervical spinal cord injury and effect of adenosine A1 receptors modulation in rats.J Appl Physiol (1985). 2019 Dec 1;127(6):1668-1676. doi: 10.1152/japplphysiol.00563.2019. Epub 2019 Oct 10. J Appl Physiol (1985). 2019. PMID: 31600096
-
Relationship Between Sleep-Disordered Breathing and Neurogenic Obesity in Adults With Spinal Cord Injury.Top Spinal Cord Inj Rehabil. 2021;27(1):84-91. doi: 10.46292/sci20-00044. Top Spinal Cord Inj Rehabil. 2021. PMID: 33814886 Free PMC article. Review.
Cited by
-
Tetraplegia is associated with increased hypoxic ventilatory response during nonrapid eye movement sleep.Physiol Rep. 2022 Sep;10(17):e15455. doi: 10.14814/phy2.15455. Physiol Rep. 2022. PMID: 36065854 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical