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Review
. 2020 Dec;15(4):461-470.
doi: 10.1016/j.jsmc.2020.08.006. Epub 2020 Oct 6.

Noninvasive Ventilation and Spinal Cord Injury

Asil Daoud  1 , Samran Haider  1 , Abdulghani Sankari  2
Affiliations
Review

Noninvasive Ventilation and Spinal Cord Injury

Asil Daoud et al. Sleep Med Clin. 2020 Dec.

Abstract

Individuals with spinal cord injury (SCI) are at increased risk of respiratory complications during wake and sleep. Sleep-disordered breathing (SDB) is commonly associated with SCI and requires an individualized approach to its management. Respiratory control plays a key role in the pathogenesis of SDB in cervical SCI. Noninvasive ventilation plays an important role in the management of respiratory complications in individuals with SCI acutely and in chronic phases. Positive airway pressure treatment may be effective in eliminating SDB and improving sleepiness symptoms, but adherence to treatment is poor and effect on long-term outcomes is questionable.

Keywords: Noninvasive ventilation; Sleep; Sleep-disordered breathing; Spinal cord injury (SCI).

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Conflict of interest statement

Disclosure This study was not industry supported. The authors have no financial conflicts of interest. The opinions expressed in this article reflect those of the authors and do not necessarily represent official views of Department of Veterans’ Affairs (VA). Dr A. Sankari is supported by the Office of Research and Development from the VA award RX002885 and from the National Heart, Lung, and Blood Institute awards HL140447 and HL130552.

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