Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Oct;38(4):328-338.
doi: 10.2337/cd19-0101.

Prediabetes Deserves More Attention: A Review

Yakubu Lawal  1 , Fatima Bello  2 , Yazid Suleiman Kaoje  2
Affiliations

Prediabetes Deserves More Attention: A Review

Yakubu Lawal et al. Clin Diabetes. 2020 Oct.

Abstract

Evidence increasingly demonstrates that prediabetes is a toxic state, as well as a risk factor for diabetes, and is associated with pathophysiological changes in several tissues and organs. Unfortunately, use of available evidence-based treatments for prediabetes is low. This review seeks to explain why prediabetes must be viewed and treated as a serious pathological entity in its own right. It offers an overview of the pathophysiology and complications of prediabetes and describes how this condition can be reversed if all treatment avenues are deployed early in its course.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Rett K, Gottwald-Hostalek U. Understanding prediabetes: definition, prevalence, burden and treatment options for an emerging disease. Curr Med Res Opin 2019;35:1529–1534 - PubMed
    1. Cefalu WT. “Prediabetes”: are there problems with this label? No, we need heightened awareness of this condition! Diabetes Care 2016;39:1472–1477 - PMC - PubMed
    1. Brannick B, Wynn A, Dagogo-Jack S. Prediabetes as a toxic environment for the initiation of microvascular and macrovascular complications. Exp Biol Med (Maywood) 2016;241:1323–1331 - PMC - PubMed
    1. Wasserman DH, Wang TJ, Brown NJ. The vasculature in prediabetes. Circ Res 2018;122:1135–1150 - PMC - PubMed
    1. Zand A, Ibrahim K, Patham B. Prediabetes: why should we care? Methodist DeBakey Cardiovasc J 2018;14:289–297 - PMC - PubMed