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. 2020 Sep 19:38:100765.
doi: 10.1016/j.nmni.2020.100765. eCollection 2020 Nov.

Predominance of Leptospira wolffii in north-central Bangladesh, 2019

S Rahman  1 , S K Paul  2 , M S Aung  3 , S Ahmed  1 , N Haque  1 , M N I Raisul  4 , J K Choity  1 , S S Nila  1 , H Ara  1 , S Roy  1 , M N A A Khan  1 , M A Hossain  5 , N Kobayashi  3
Affiliations

Predominance of Leptospira wolffii in north-central Bangladesh, 2019

S Rahman et al. New Microbes New Infect. .

Abstract

Leptospira was detected in 48.9% of blood samples from 182 febrile patients in north-central Bangladesh in 2019. Most Leptospira were classified as L. wolffii (93%) on the basis of phylogenetic analysis of 16S ribosomal RNA genes, while others were assigned to L. borgpetersenii and L. meyeri.

Keywords: 16S rRNA; Bangladesh; Leptospira borgpetersenii; Leptospira meyeri; Leptospira wolffii.

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Figures

Fig. 1
Fig. 1
Phylogenetic dendrogram based on partial 16S ribosomal RNA gene sequences of Leptospira constructed by maximum likelihood method using MEGA6 programme, following alignment with Clustal W algorithm. Tree was statistically supported by bootstrapping with 1000 replicates; phylogenetic distances were measured by Kimura two-parameter model with uniform rates among sites. Samples we analysed are indicated by solid circles; previous study in Mymensingh, Bangladesh [5], uses diamonds. Bootstrap values more than 80% are shown. Scale bar represents genetic distance, i.e. number of substitution per site. Subclusters are shown at right using designation in parentheses (P1, P2, S1/S2) by Guglielmini et al. [12] along with former designations (pathogenic, intermediate, nonpathogenic). Cluster of L. wolffii and closely related species to L. wolffii in P2 subclade is shown by vertical line.
See this image and copyright information in PMC

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