Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Oct 7;7(10):ofaa475.
doi: 10.1093/ofid/ofaa475. eCollection 2020 Oct.

Disseminated Mycobacterium bovis Infection Complicated by Meningitis and Stroke: A Case Report

Katherine M Clifford  1 , John D Szumowski  2
Affiliations
Case Reports

Disseminated Mycobacterium bovis Infection Complicated by Meningitis and Stroke: A Case Report

Katherine M Clifford et al. Open Forum Infect Dis. .

Abstract

We describe a case of a 19-year-old female presenting with Mycobacterium bovis meningitis, a rarely encountered infection. We discuss the use of pyrosequencing to aid in prompt diagnosis of M. bovis infection, as well as treatment strategies and challenges given the organism's intrinsic resistance to pyrazinamide.

Keywords: bovis; meningitis; tuberculosis.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Contrast-enhanced computed tomography imaging on presentation demonstrating tuberculomas (arrows) in the left frontal lobe and left cerebellar vermis.
Figure 2.
Figure 2.
Diffusion-weighted image (DWI) magnetic resonance imaging sequence demonstrating acute ischemic infarct affecting the right basal ganglia. Areas of restricted diffusion were visualized in the right corona radiata, posterior limb of the internal capsule, and putamen, as well as in the left anterior centrum semiovale.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Thwaites GE, van Toorn R, Schoeman J. Tuberculous meningitis: more questions, still too few answers. Lancet Neurol 2013; 12:999–1010. - PubMed
    1. Stadelman AM, Ellis J, Samuels THA, et al. Treatment outcomes in adult tuberculous meningitis: a systematic review and meta-analysis. Open Forum Infect Dis 2020; 7:ofaa257. - PMC - PubMed
    1. Griffith AS. Bovine tuberculosis in man. Tuberculosis 1937; 18:529–43.
    1. Novick N. The incidence of bovine infection in tuberculous meningitis. J Med Res 1920; 41:239–46. - PMC - PubMed
    1. Dankner WM, Waecker NJ, Essey MA, et al. Mycobacterium bovis infections in San Diego: a clinicoepidemiologic study of 73 patients and a historical review of a forgotten pathogen. Medicine (Baltimore) 1993; 72:11–37. - PubMed

Publication types