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Case Reports
. 2020 Oct 6;7(1):112-115.
doi: 10.1080/23320885.2020.1824614.

Pseudoangiomatous stromal hyperplasia: an unsuspected cause of anisomasty

Fabio Santanelli di Pompeo  1 , Michail Sorotos  2 , Francesca Passarelli  3 , Valeria Berrino  1 , Guido Firmani  1 , Harm Winters  4 , Guido Paolini  1
Affiliations
Case Reports

Pseudoangiomatous stromal hyperplasia: an unsuspected cause of anisomasty

Fabio Santanelli di Pompeo et al. Case Reports Plast Surg Hand Surg. .

Abstract

Breast asymmetry can be congenital or developmental, however a tumorous growth may be the cause of this condition after puberty. A 19-year-old female presented with a slowly developing breast asymmetry pre-operatively diagnosed as Pseudoangiomatous Stromal Hyperplasia (PASH). The patient underwent tumour excision with breast gland remodelling. Postoperative course was uneventful.

Keywords: Breast asymmetry; PASH; Pseudoangiomatous stromal hyperplasia; benign tumour.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
Preoperative frontal (center), left oblique (left side), right oblique (right side) pictures.
Figure 2.
Figure 2.
Intraoperative view showing well-encapsulated tumorous growth with a distinct dissection plane (left). Photo of tumorous growth upon removal (right).
Figure 3.
Figure 3.
Left side: Proliferation of stromal elements (fibroblastic/myofibroblastic) mixed with breast ducts (10× HE). Right side: Dense keloid-like stroma has anastomosing pattern of slit-like clefts (empty spaces) lined by single layer of flat spindle cells simulating vascular spaces CD34 + (10× CD34).
Figure 4.
Figure 4.
Postoperative frontal (center), left oblique (left side), right oblique (right side) pictures.
See this image and copyright information in PMC

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