In the Age of COVID: Genomic Changes Over the Lifespan Help Explain Severe SARS-CoV-2 Disease
- PMID: 33134610
- PMCID: PMC7584415
- DOI: 10.1016/j.jacbts.2020.10.004
In the Age of COVID: Genomic Changes Over the Lifespan Help Explain Severe SARS-CoV-2 Disease
Keywords: COVID-19; age; cardiovascular; endothelial cells.
Conflict of interest statement
Both authors have reported that they have no relationships relevant to the contents of this paper to disclose.
Comment on
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Cardiorenal Tissues Express SARS-CoV-2 Entry Genes and Basigin (BSG/CD147) Increases With Age in Endothelial Cells.JACC Basic Transl Sci. 2020 Nov;5(11):1111-1123. doi: 10.1016/j.jacbts.2020.09.010. Epub 2020 Oct 9. JACC Basic Transl Sci. 2020. PMID: 33073064 Free PMC article.
References
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- Wang K., Chen W., Zhou Y.-S. SARS-CoV-2 invades host cells via a novel route: CD147-spike protein. bioRxiv. 2020 http://biorxiv.org/content/early/2020/03/14/2020.03.14.988345.abstract 2020.03.14.988345. Available at: Accessed October 10, 2020. - PMC - PubMed
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- Shilts J., Wright G.J. No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor. bioRxiv. 2020 http://biorxiv.org/content/early/2020/07/26/2020.07.25.221036.abstract 2020.07.25.221036. Available at: Accessed October 10, 2020. - PMC - PubMed
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- Bian H., Zheng Z.-H., Wei D. Meplazumab treats COVID-19 pneumonia: an open-labelled, concurrent controlled add-on clinical trial. medRxiv. 2020 http://medrxiv.org/content/early/2020/09/27/2020.03.21.20040691.abstract 2020.03.21.20040691. Available at: Accessed October 10, 2020.
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