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Clinical Trial
. 1987;8(2):203-11.
doi: 10.1016/0891-4222(87)90004-7.

Effects of fenfluramine on the behavior of autistic individuals

G Groden  1 , J Groden, M Dondey, T Zane, S M Pueschel, W Veliceur
Affiliations
Clinical Trial

Effects of fenfluramine on the behavior of autistic individuals

G Groden et al. Res Dev Disabil. 1987.

Abstract

The present report, part of a national, multicenter study to investigate the effects of fenfluramine on autistic behavior, describes findings on four autistic children ranging in age from 7 to 20 years. Additional performance and parental observation measures apart from those of the multicenter study are included. Results of this study which indicated no significant side effects, a reduction in some deviant behaviors and an improvement in activity level/attention span, provide support for earlier reports. The possibility that fenfluramine's apparently positive effects might be to simply reduce inappropriate behaviors via lethargy was examined and not supported.

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