Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Mar 1;1867(3):165999.
doi: 10.1016/j.bbadis.2020.165999. Epub 2020 Nov 1.

The risk of COVID-19 for pregnant women: Evidences of molecular alterations associated with preeclampsia in SARS-CoV-2 infection

Walter Orlando Beys-da-Silva  1 , Rafael Lopes da Rosa  2 , Lucélia Santi  3 , Emanuela Fernanda Tureta  2 , Paula Barros Terraciano  4 , Jorge Almeida Guimarães  5 , Eduardo Pandolfi Passos  4 , Markus Berger  6
Affiliations

The risk of COVID-19 for pregnant women: Evidences of molecular alterations associated with preeclampsia in SARS-CoV-2 infection

Walter Orlando Beys-da-Silva et al. Biochim Biophys Acta Mol Basis Dis. .
No abstract available

Keywords: COVID-19; Coronavirus; Preeclampsia; Pregnant women; SARS-CoV-2.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Network of DEG associated to preeclampsia during SARS-CoV-2 infection. Significant GSEA cluster/pathways are presented in rectangle (blue to yellow in color scale) and genes upregulated (red) or downregulated (green) are represented in circles. A gene set was considered significantly enriched with FDR < 0.25 for the normalized enrichment score (NES). The network was constructed using Cytoscape 3.8.2 software [15].
See this image and copyright information in PMC

References

    1. Dashraath P, Lin J, Wong J, et al. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. 2020 [cited 2020 May 24];Available from: doi:10.1016/j.ajog.2020.03.021. - DOI - PMC - PubMed
    1. Lan J, Ge J, Yu J, et al. Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor. 2020 [cited 2020 Apr 14];Available from: doi:10.1038/s41586-020-2180-5. - DOI - PubMed
    1. Zhang H., Penninger J.M., Li Y., Zhong N., Slutsky A.S. Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target. Intensive Care Med. 2020;46(4):586–590. - PMC - PubMed
    1. Di Mascio D., Khalil A., Saccone G., et al. Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis. Am. J. Obstet. Gynecol. MFM. 2020;2(2) doi: 10.1016/j.ajogmf.2020.100107. - DOI - PMC - PubMed
    1. Liu D., Li L., Wu X., et al. Pregnancy and perinatal outcomes of women with coronavirus disease (COVID-19) pneumonia: a preliminary analysis. AJR. 2020;215 www.ajronline.org Available from: (Internet, cited 2020 Aug 1) - PubMed

LinkOut - more resources