Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Nov;587(7834):374-376.
doi: 10.1038/d41586-020-03070-1.

Interferon deficiency can lead to severe COVID

Eric Meffre, Akiko Iwasaki
Comment

Interferon deficiency can lead to severe COVID

Eric Meffre et al. Nature. 2020 Nov.
No abstract available

Keywords: Immunology; Medical research; SARS-CoV-2.

PubMed Disclaimer

Comment on

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19.
    Bastard P, Rosen LB, Zhang Q, Michailidis E, Hoffmann HH, Zhang Y, Dorgham K, Philippot Q, Rosain J, Béziat V, Manry J, Shaw E, Haljasmägi L, Peterson P, Lorenzo L, Bizien L, Trouillet-Assant S, Dobbs K, de Jesus AA, Belot A, Kallaste A, Catherinot E, Tandjaoui-Lambiotte Y, Le Pen J, Kerner G, Bigio B, Seeleuthner Y, Yang R, Bolze A, Spaan AN, Delmonte OM, Abers MS, Aiuti A, Casari G, Lampasona V, Piemonti L, Ciceri F, Bilguvar K, Lifton RP, Vasse M, Smadja DM, Migaud M, Hadjadj J, Terrier B, Duffy D, Quintana-Murci L, van de Beek D, Roussel L, Vinh DC, Tangye SG, Haerynck F, Dalmau D, Martinez-Picado J, Brodin P, Nussenzweig MC, Boisson-Dupuis S, Rodríguez-Gallego C, Vogt G, Mogensen TH, Oler AJ, Gu J, Burbelo PD, Cohen JI, Biondi A, Bettini LR, D'Angio M, Bonfanti P, Rossignol P, Mayaux J, Rieux-Laucat F, Husebye ES, Fusco F, Ursini MV, Imberti L, Sottini A, Paghera S, Quiros-Roldan E, Rossi C, Castagnoli R, Montagna D, Licari A, Marseglia GL, Duval X, Ghosn J; HGID Lab; NIAID-USUHS Immune Response to COVID Group; COVID Clinicians; COVID-STORM Clinicians; Imagine COVID Group; French COVID Cohort Study Group; Milieu Intérieur Consortium; CoV-Contact Cohort; Amsterdam UMC Covid-19… See abstract for full author list ➔ Bastard P, et al. Science. 2020 Oct 23;370(6515):eabd4585. doi: 10.1126/science.abd4585. Epub 2020 Sep 24. Science. 2020. PMID: 32972996 Free PMC article.
  • Susceptibility to severe COVID-19.
    Beck DB, Aksentijevich I. Beck DB, et al. Science. 2020 Oct 23;370(6515):404-405. doi: 10.1126/science.abe7591. Science. 2020. PMID: 33093097 No abstract available.

References

    1. Richardson, S. et al. J. Am. Med. Assoc. 323, 2052–2059 (2020). - DOI
    1. Grasselli, G. et al. J. Am. Med. Assoc. 323, 1574–1581 (2020). - DOI
    1. Zhang, Q. et al. Science 370, eabd4570 (2020). - PubMed - DOI
    1. Bastard, P. et al. Science 370, eabd4585 (2020). - PubMed - DOI
    1. Schoggins, J. W. et al. Nature 472, 481–485 (2011). - PubMed - DOI - PMC

LinkOut - more resources