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. 2021 Mar;24(1):3-20.
doi: 10.1007/s11019-020-09984-x. Epub 2020 Nov 3.

Back to WHAT? The role of research ethics in pandemic times

Jan Helge Solbakk  1 , Heidi Beate Bentzen  2   3 , Søren Holm  2   4 , Anne Kari Tolo Heggestad  2   5 , Bjørn Hofmann  2   6 , Annette Robertsen  2   7   8 , Anne Hambro Alnæs  2 , Shereen Cox  2 , Reidar Pedersen  2 , Rose Bernabe  2   9
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Back to WHAT? The role of research ethics in pandemic times

Jan Helge Solbakk et al. Med Health Care Philos. 2021 Mar.

Abstract

The Covid-19 pandemic creates an unprecedented threatening situation worldwide with an urgent need for critical reflection and new knowledge production, but also a need for imminent action despite prevailing knowledge gaps and multilevel uncertainty. With regard to the role of research ethics in these pandemic times some argue in favor of exceptionalism, others, including the authors of this paper, emphasize the urgent need to remain committed to core ethical principles and fundamental human rights obligations all reflected in research regulations and guidelines carefully crafted over time. In this paper we disentangle some of the arguments put forward in the ongoing debate about Covid-19 human challenge studies (CHIs) and the concomitant role of health-related research ethics in pandemic times. We suggest it might be helpful to think through a lens differentiating between risk, strict uncertainty and ignorance. We provide some examples of lessons learned by harm done in the name of research in the past and discuss the relevance of this legacy in the current situation.

Keywords: Challenge studies; Covid-19; Exceptionalism; Research ethics; Uncertainty; Vulnerability.

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