Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Sep;25(3):313-318.
doi: 10.1007/s10006-020-00918-8. Epub 2020 Nov 3.

The impact of lip-split mandibulotomy on patients treated for pT2 oral tongue squamous cell carcinoma: a study of 224 patients

Panagiotis Stathopoulos  1 , Maria Elli Doufexi Kaplani  2 , Nikolaos Kostis  3 , Dimosthenis Igoumenakis  4 , William P Smith  5
Affiliations

The impact of lip-split mandibulotomy on patients treated for pT2 oral tongue squamous cell carcinoma: a study of 224 patients

Panagiotis Stathopoulos et al. Oral Maxillofac Surg. 2021 Sep.

Abstract

Background: Head and neck surgeons often face a challenge in order to achieve adequate three-dimensional resection of tumours in the oral cavity, especially in the dentate patient.

Methods: We compared the outcomes of lip-split mandibulotomy and trans-oral access, respectively, in patients treated for primary pT2 oral tongue SCC with regard to the status of the resection margins and the incidence of tumour recurrence.

Results: Multivariate analysis showed a non-significant effect of the surgical technique used to the reported recurrence, F(1, 224) = 0.350, p = .555 and a significant effect on the margins achieved F(1, 224) = 11.381, p = .001.

Conclusions: Defects after excision of larger and more posterior tumours that are going to be reconstructed with free flaps represent a more probable indication for using an osteotomy access technique. Lip-split mandibulotomy is a low-morbidity technique which can deliver a sound oncological outcome and can be relatively easily taught to less experienced surgeons.

Keywords: Lip-spilt mandibulotomy; Oral cancer; Recurrence; Resection margins.

PubMed Disclaimer

References

    1. Ong HS, Gokavarapu S, Tian Z, Li J, Cao W, Zhang CP (2017) Does a mandibular access osteotomy improve survival in pT2 oral tongue cancers? Retrospective study at a single institution. Int J Oral Maxillofac Surg 47:289–295. https://doi.org/10.1016/j.ijom.2017.08.010 - DOI - PubMed
    1. Kolokythas A, Eisele DW, El-Sayed I, Schmidt BL (2009) Mandibular osteotomies for access to select parapharyngeal space neoplasms. Head Neck 31(1):102–110 - DOI
    1. Butlin HT Diseases of the tongue. London: Cassell; 1885. 331
    1. Spiro RH, Gerold FP, Strong EW (1981) Mandibular “swing” approach for oral and oropharyngeal tumors. Head Neck Surg 3:371–378 - DOI
    1. McCann KJ, Irish JC, Gullane PJ, Holmes H, Brown DH, Rotstein L (1994) Complications associated with rigid fixation of mandibulotomies. J Otolaryngol 23(3):210–215 - PubMed

LinkOut - more resources