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. 2020 Oct 30;17(21):7997.
doi: 10.3390/ijerph17217997.

Increasing HPV Vaccination Uptake among Adolescents: A Systematic Review

Anna Acampora  1 , Adriano Grossi  1 , Andrea Barbara  1 , Vittoria Colamesta  1   2 , Francesco Andrea Causio  1 , Giovanna Elisa Calabrò  1   3 , Stefania Boccia  1   4 , Chiara de Waure  5
Affiliations

Increasing HPV Vaccination Uptake among Adolescents: A Systematic Review

Anna Acampora et al. Int J Environ Res Public Health. .

Abstract

Human Papillomavirus (HPV) vaccination is a well-known fundamental strategy in the prevention of cervical cancer, as it is always caused by HPV infection. In fact, primary prevention of the infection corresponds to primary prevention of HPV-related cancers and other diseases. Since an effective prevention at the population level is the final goal, it is mandatory for healthcare systems to achieve a high HPV vaccination coverage among the adolescents to reduce the circulation of the virus and the burden of HPV-related diseases. This research identified, through a systematic literature review, 38 papers on strategies adopted to increase HPV vaccination coverage among adolescents. The evaluated strategies targeted adolescents/parents and/or healthcare providers and could be grouped in three main types: (1) reminder-based, (2) education, information, and communication activities, and (3) multicomponent strategies. Several types of strategy, such as those relied only on reminders and integrating different interventions, showed a positive impact on vaccination coverage. Nonetheless, the heterogeneity of the interventions suggests the importance to adapt such strategies to the specific national/local contexts to maximize vaccination coverage.

Keywords: HPV vaccination; increasing coverage; systematic review.

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Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Figures

Figure 1
Figure 1
Flow chart of article selection process. Modified from: Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group (2009). Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. BMJ 2009; 339:b2535, doi: 10.1136/bmj.b2535 [23].
See this image and copyright information in PMC

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