Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Oct 30;10(11):888.
doi: 10.3390/diagnostics10110888.

Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-FNA) with Image Enhancement

Masahiro Itonaga  1 , Reiko Ashida  1 , Masayuki Kitano  1
Affiliations
Review

Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-FNA) with Image Enhancement

Masahiro Itonaga et al. Diagnostics (Basel). .

Abstract

Although endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is useful in the differential diagnosis of solid pancreatic lesions, lymph nodes, and liver lesions, inadequate sampling may result in an incorrect pathological diagnosis. The accuracy of EUS for the evaluation of pancreatobiliary lesions may be increased by image enhancement technologies, including contrast-enhanced harmonic (CH)-EUS and EUS-elastography. These methods can provide information that complement EUS-FNA for the diagnosis and staging of pancreatobiliary cancer, and can help to identify the EUS-FNA target, reducing the requirement for repeat FNA.

Keywords: CH-EUS; EUS-FNA; EUS-elastography.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Targeting EUS-FNA with CH-EUS. (a) Fundamental B mode endoscopic ultrasonogram showing a low echoic mass. (b) CH-EUS image showing a non-enhancing area within the tumor. (c) EUS-FNA with CH-EUS avoiding the non-enhancing area.
Figure 2
Figure 2
Targeting EUS-FNA with EUS-elastography. (a) Fundamental B mode endoscopic ultrasonogram showing a low echoic mass. (b) EUS-elastography image showing no distortion on low echo area and surrounding tissue. (c) EUS-FNA with EUS-elastography targeting the harder area.
See this image and copyright information in PMC

References

    1. Vilmann P., Jacobsen G.K., Henriksen F.W., Hancke S. Endoscopic ultrasonography with guided fine needle aspiration biopsy in pancreatic disease. Gastrointest. Endosc. 1992;38:172–173. doi: 10.1016/S0016-5107(92)70385-X. - DOI - PubMed
    1. Olyaee M., Jani B.S., Rzouq F., Saligram S., Lim D., Rastogi A., Bonino J. Endoscopic ultrasound-guided fine-needle aspiration of pancreatic lesions: A systematic review of technical and procedural variables. N. Am. J. Med Sci. 2016;8:1–11. doi: 10.4103/1947-2714.175185. - DOI - PMC - PubMed
    1. Lee Y.N., Moon J.H., Kim H.K., Choi H.J., Choi M.H., Kim D.C., Lee T.H., Cha S.-W., Cho Y.D., Park S.-H. Core biopsy needle versus standard aspiration needle for endoscopic ultrasound-guided sampling of solid pancreatic masses: A randomized parallel-group study. Endoscopy. 2014;46:1056–1062. doi: 10.1055/s-0034-1377558. - DOI - PubMed
    1. Kudo T., Kawakami H., Hayashi T., Yasuda I., Mukai T., Inoue H., Katanuma A., Kawakubo K., Ishiwatari H., Doi S., et al. High and low negative pressure suction techniques in EUS-guided fine-needle tissue acquisition by using 25-gauge needles: A multicenter, prospective, randomized, controlled trial. Gastrointest. Endosc. 2014;80:1030–1037.e1. doi: 10.1016/j.gie.2014.04.012. - DOI - PubMed
    1. Matynia A.P., Schmidt R.L., Barraza G., Layfield L.J., Siddiqui A.A., Adler D.G. Impact of rapid on-site evaluation on the adequacy of endoscopic-ultrasound guided fine-needle aspiration of solid pancreatic lesions: A systematic review and meta-analysis. J. Gastroenterol. Hepatol. 2014;29:697–705. doi: 10.1111/jgh.12431. - DOI - PubMed

LinkOut - more resources