Solitary sclerotic fibroma on the thigh

Abstract

Sclerotic fibroma is a rare fibrous tumor of the skin associated with Cowden's disease. In 1989, Rapini described sclerotic fibroma without Cowden's disease as solitary sclerotic fibroma of the skin. It is a solid, well-circumscribed, slow-growing nodular tumor and it looks similar to a keloid scar. Consequently, it is extremely difficult to make a differential diagnosis of solitary sclerotic fibroma with keloid scar based on clinical findings only. The authors report a case of solitary sclerotic fibroma arising at the left lateral thigh of a 25-year-old man.

Keywords: Diagnosis, differential; Fibroma; Keloid; Skin neoplasms.

Fig. 1.

Preoperative photograph showing a 3 × 3 × 1.5 cm sized mass on left lateral thigh area.

Fig. 2.

Postoperative photograph 10 days after surgery.

Fig. 3.

Histopathologic examination shows a well-defined, hypocellular intradermal fibrotic nodule (H&E, ×10).

Fig. 4.

Immunohistopathologic examination shows abundant, dense hyalinized collagen bundles (trichrome stain, ×10).

Fig. 5.

Storiform patterns of collagenous bundle that were separated by prominent clefts (H&E, ×300).