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. 2020 Nov-Dec;34(6):3589-3595.
doi: 10.21873/invivo.12203.

Clinical Outcomes of Acute Myocardial Infarction Patients With a History of Malignant Tumor

Masashi Nozaka  1 , Hiroaki Yokoyama  1 , Kazutaka Kitayama  1 , Daiki Nagawa  1 , Misato Hamadate  1 , Naotake Miura  1 , Yosuke Kawamura  1 , Masamichi Nakata  1 , Fumie Nishizaki  1 , Kenji Hanada  1 , Takashi Yokota  1 , Masahiro Yamada  1 , Hirofumi Tomita  2
Affiliations

Clinical Outcomes of Acute Myocardial Infarction Patients With a History of Malignant Tumor

Masashi Nozaka et al. In Vivo. 2020 Nov-Dec.

Abstract

Background: Little is known about the clinical outcomes of acute myocardial infarction (AMI) in patients with a history of malignant tumor (MT).

Patients and methods: We retrospectively studied 1,295 consecutive patients with AMI who underwent primary percutaneous coronary intervention within 24 hours of onset. The patients were divided into two groups: those with a history of MT (MT group, n=50) and those without (non-MT group, n=1,245).

Results: The MT group was older, and had lower hemoglobin, total protein, and albumin levels. All-cause mortality and re-admission rates due to acute decompensated heart failure (ADHF) were significantly higher in the MT group. Multivariate analysis showed that a history of MT was an independent predictor for all-cause mortality and re-admission due to ADHF.

Conclusion: The clinical outcomes of patients with AMI with a history of MT are poor, and a history of MT is an independent predictor for all-cause mortality and re-admission due to ADHF. These patients may need careful risk management for heart failure to avoid re-admissions due to ADHF.

Keywords: Malignant tumor; acute myocardial infarction; heart failure.

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Conflict of interest statement

The Authors declare no conflicts of interest associated with this article.

Figures

Figure 1
Figure 1. Kaplan-Meier curves for all-cause mortality (A), cardiac death (B), non-cardiac death (C), and re-admission due to acute decompensated heart failure (D) in patients with acute myocardial infarction with (MT) and without (non-MT) malignant tumor
See this image and copyright information in PMC

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